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mnemonics for human translation factors
30-Aug-2013, 05:02 PM
Post: #1
mnemonics for human translation factors
The terminology of translation factors in humans is a nightmare for a person with a less than perfect memory. I constantly get in trouble trying to recall what some e-i-f-2 or 3-b or e-alpha/beta is doing. Any ideas on how to help to remember who does what in eukaryotic translation? I have a suggestion for eIF2, 2 looks a bit like a tRNA that is bound to mRNA. If you have any other suggestions, please post them into this thread.


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primus inter pares Angel
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04-Oct-2013, 11:00 AM
Post: #2
RE: mnemonics for human translation factors
Here's the one I use with my students - a bit bizarre, but might help:

1 and 1A = 1nit1Ation codon selection
2/Two = “T”ernary complex or “T”RNA (also G”T”P binding needed)
3 = Ribosome 3inding/3ridging (but subunit specific ones will be hard!)
4A = Helic”A”se, 4B makes it “B”etter, 4H “H”elps too
4E = the letter "e" looks a bit like a cap-binding protein – also binds 5’ “E”nd
4G = “G”reat big scaffold protein – “G”roups/”G”athers everything together
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05-Oct-2013, 06:56 PM
Post: #3
RE: mnemonics for human translation factors
Thank you, Mark, that's great. When I get some time, I will try to make a figure and will post it here. Anything for 5?

primus inter pares Angel
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